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PQI: Neratinib (Nerlynx®) Diarrhea Management

Neratinib (Nerlynx®) Diarrhea Management

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Last Updated: October 10, 2023

By: Eric Dallara, RPh

About this PQI

Diarrhea is the main toxicity of neratinib treatment occurring in 95% of patients in the ExteNET trial on the neratinib arm in which antidiarrheal prophylaxis was not protocol specified. 1 Various prevention and treatment strategies for diarrhea have been studied and will be discussed in this document.

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