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Managing TKI-Induced Hand-Foot Skin Reaction

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Last Updated: October 6, 2023

By: Jessie Modlin, PharmD, BCOP

About this PQI

Hand-foot skin reaction (HFSR) is one of the most common cutaneous adverse events caused by protein tyrosine kinase inhibitors (TKIs). It is important to prevent and manage this side effect in an effort to avoid dose reductions or treatment interruptions and reduced quality of life.

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Essentially, it’s a tool to improve patient care by sharing best practices in oncology care. Consider this standardized, peer-review clinical guidance to oncology healthcare teams, enabling you and your team to consistently deliver high-quality care to your patients.

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