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The purpose of this PQI is to discuss the option of using isatuximab-irfc with pomalidomide and dexamethasone in patients with relapsed/refractor multiple myeloma (RRMM) who have received at least 2 prior therapies including lenalidomide and a proteosome inhibitor or in combination with carfilzomib and dexamethasone in patients with RRMM who have received 1 to 3 prior lines of therapy.